Phenotypes associated with this allele

• Allele Symbol: Mpzl1^em1Ambt
• Allele Name: endonuclease-mediated mutation 1, Anton M Bennett
• Allele ID: MGI:6507873
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mpzl1^em1Ambt/Mpzl1^em1Ambt	C57BL/6J-Mpzl1^em1Ambt	MGI:6507957
cx2	Mpzl1^em1Ambt/Mpzl1^em1Ambt Ptpn11^tm4.2Bgn/Ptpn11^tm4.2Bgn	B6.Cg-Mpzl1^em1Ambt Ptpn11^tm4.2Bgn	MGI:6507959

Genotype
MGI:6507957

hm1

• Allelic Composition: Mpzl1^em1Ambt/Mpzl1^em1Ambt
• Genetic Background: C57BL/6J-Mpzl1^em1Ambt

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:301775 )

N • normal heart weight (HW) to body weight (BW) and tibia length (TL) ratios at age 20 weeks and interventricular septum wall (IVS) and left ventricular posterior wall (LVPW) thickness and ejection fraction (EF) at age 16 weeks

growth/size/body

growth/size/body region phenotype ( J:301775 )

N • normal organ weight and heart weight (HW) to body weight (BW) and tibia length (TL) ratios at age 20 weeks

slow postnatal weight gain ( J:301775 )

mortality/aging

mortality/aging ( J:301775 )

N • mice born at normal Mendelian ratio

reproductive system

reproductive system phenotype ( J:301775 )

N • fertile

Genotype
MGI:6507959

cx2

• Allelic Composition: Mpzl1^em1Ambt/Mpzl1^em1Ambt; Ptpn11^tm4.2Bgn/Ptpn11^tm4.2Bgn
• Genetic Background: B6.Cg-Mpzl1^em1Ambt Ptpn11^tm4.2Bgn

cardiovascular system

cardiovascular system phenotype ( J:301775 )

N • normal heart weight (HW) and HW to body weight (BW) and tibia length (TL) ratios and interventricular septum wall (IVS) and left ventricular posterior wall (LVPW) thickness at age 16 weeks

N • no myocardial fibrosis

growth/size/body

growth/size/body region phenotype ( J:301775 )

N • normal heart weight (HW) and HW to body weight (BW) and tibia length (TL) ratios at age 16 weeks

slow postnatal weight gain ( J:301775 )