About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cmtm4em1Wlh
endonuclease-mediated mutation1, WenLing Han
MGI:6457028
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Cmtm4em1Wlh/Cmtm4em1Wlh involves: C57BL/6J MGI:6458554


Genotype
MGI:6458554
hm1
Allelic
Composition
Cmtm4em1Wlh/Cmtm4em1Wlh
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cmtm4em1Wlh mutation (0 available); any Cmtm4 mutation (11 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• increased incidence of bent midpiece
• increased incidence of backward curved heads

reproductive system
N
• normal spermatogonial, primary spermatocyte, round spermatid, elongated spermatid, and Sertoli cell morphology in seminiferous tubules
• normal testis/body weight ratio
• normal cauda epididymal sperm content
• normal serum testosterone level
• increased incidence of bent midpiece
• increased incidence of backward curved heads
• low fertilization ability of spermatozoa in vitro
• fewer pregnancies after 2 months cohabitation with WT females





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory