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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Zrsr2em1Alfon
endonuclease-mediated mutation 1, Alfonso Gutierrez-Adan
MGI:6451794
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Zrsr2-ps1em1Alfon/Zrsr2-ps1+
Zrsr2em1Alfon/Zrsr2+ 		involves: C57BL/6 * CBA MGI:6693495
cx2
 		Zrsr2-ps1em1Alfon/Zrsr2-ps1+
Zrsr2em1Alfon/Y 		involves: C57BL/6 * CBA MGI:6693496


Genotype
MGI:6693495
cx1
Allelic
Composition		 Zrsr2-ps1em1Alfon/Zrsr2-ps1+
Zrsr2em1Alfon/Zrsr2+
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zrsr2em1Alfon mutation (0 available); any Zrsr2 mutation (13 available)
Zrsr2-ps1em1Alfon mutation (0 available); any Zrsr2-ps1 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality before implantation, complete penetrance ( J:292025 )
• arrest at the 2-cell stage when Zrsr2em1Alfon is inherited maternally and Zrsr1em1Alfon is inherited paternally




Genotype
MGI:6693496
cx2
Allelic
Composition		 Zrsr2-ps1em1Alfon/Zrsr2-ps1+
Zrsr2em1Alfon/Y
Genetic
Background		 involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zrsr2em1Alfon mutation (0 available); any Zrsr2 mutation (13 available)
Zrsr2-ps1em1Alfon mutation (0 available); any Zrsr2-ps1 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality before implantation, complete penetrance ( J:292025 )
• arrest at the 2-cell stage when Zrsr2em1Alfon is inherited maternally and Zrsr1em1Alfon is inherited paternally




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory