Zrsr2^em1Alfon
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zrsr2^em1Alfon
• Name: zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2; endonuclease-mediated mutation 1, Alfonso Gutierrez-Adan
• MGI ID: MGI:6451794
• Synonyms: Zrsr2^mu, Zrsr2^mu3
• Gene: Zrsr2 Location: ChrX:162718439-162741657 bp, - strand Genetic Position: ChrX, 75.99 cM
• Alliance: Zrsr2^em1Alfon page

Mutation origin

• Strain of Origin: (C57BL/6 x CBA)F1

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated a 25 nucleotide deletion in exon 10, resulting in a nonsense mutation in the second zinc finger motif of the gene. (J:292025)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zrsr2 Mutation: 13 strains or lines available

References

• Original: J:292025 Gomez-Redondo I, et al., Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion. Int J Mol Sci. 2020 Jun 9;21(11):4115
• All: 1 reference(s)