Phenotypes associated with this allele

• Allele Symbol: Plekha5^em1(IMPC)Tcp
• Allele Name: endonuclease-mediated mutation 1, The Centre for Phenogenomics
• Allele ID: MGI:6414535
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plekha5^em1(IMPC)Tcp/Plekha5^em1(IMPC)Tcp	C57BL/6NCrl-Plekha5^em1(IMPC)Tcp/Tcp	MGI:7415013

Genotype
MGI:7415013

hm1

• Allelic Composition: Plekha5^em1(IMPC)Tcp/Plekha5^em1(IMPC)Tcp
• Genetic Background: C57BL/6NCrl-Plekha5^em1(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Plekha5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired pupillary reflex ( J:211773 )

IMPC - TCP

increased startle reflex ( J:211773 )

♀

IMPC - TCP

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

♂

IMPC - TCP

abnormal retina blood vessel morphology ( J:211773 )

IMPC - TCP

cornea vascularization ( J:211773 )

IMPC - TCP

growth/size/body

enlarged urinary bladder ( J:211773 )

♂

IMPC - TCP

increased spleen weight ( J:211773 )

♂

IMPC - TCP

hematopoietic system

increased spleen weight ( J:211773 )

♂

IMPC - TCP

decreased mean corpuscular hemoglobin ( J:211773 )

♂

IMPC - TCP

immune system

increased spleen weight ( J:211773 )

♂

IMPC - TCP

enlarged lymph nodes ( J:211773 )

♂

IMPC - TCP

integument

abnormal skin morphology ( J:211773 )

♂

IMPC - TCP

nervous system

abnormal optic disk morphology ( J:211773 )

IMPC - TCP

pigmentation

abnormal iris pigmentation ( J:211773 )

IMPC - TCP

renal/urinary system

enlarged urinary bladder ( J:211773 )

♂

IMPC - TCP

vision/eye

impaired pupillary reflex ( J:211773 )

IMPC - TCP

abnormal optic disk morphology ( J:211773 )

IMPC - TCP

abnormal iris morphology ( J:211773 )

IMPC - TCP

abnormal iris pigmentation ( J:211773 )

IMPC - TCP

abnormal placement of pupils ( J:211773 )

♂

IMPC - TCP

irregularly shaped pupil ( J:211773 )

IMPC - TCP

mydriasis ( J:211773 )

IMPC - TCP

iris synechia ( J:211773 )

IMPC - TCP

abnormal cornea morphology ( J:211773 )

IMPC - TCP

cornea vascularization ( J:211773 )

IMPC - TCP

abnormal lens morphology ( J:211773 )

IMPC - TCP

fused cornea and lens ( J:211773 )

IMPC - TCP

persistence of hyaloid vascular system ( J:211773 )

IMPC - TCP

narrow eye opening ( J:211773 )

IMPC - TCP

abnormal retina morphology ( J:211773 )

IMPC - TCP

abnormal retina vasculature morphology ( J:211773 )

♂

IMPC - TCP

abnormal retina blood vessel morphology ( J:211773 )

IMPC - TCP