Phenotypes associated with this allele

• Allele Symbol: Mpp1^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:6399894
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mpp1^em1(IMPC)Ccpcz/Mpp1^em1(IMPC)Ccpcz	C57BL/6NCrl-Mpp1^em1(IMPC)Ccpcz/Ccpcz	MGI:7768382

Genotype
MGI:7768382

hm1

• Allelic Composition: Mpp1^{em1(IMPC)Ccpcz}/Mpp1^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Mpp1^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Mpp1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body weight ( J:211773 )

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

increased CD4-positive, alpha-beta T cell number ( J:211773 )

IMPC - CCP-IMG

decreased effector memory T-helper cell number ( J:211773 )

IMPC - CCP-IMG

increased effector memory T-helper cell number ( J:211773 )

♂

IMPC - CCP-IMG

increased T-helper cell number ( J:211773 )

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♂

IMPC - CCP-IMG

immune system

increased CD4-positive, alpha-beta T cell number ( J:211773 )

IMPC - CCP-IMG

decreased effector memory T-helper cell number ( J:211773 )

IMPC - CCP-IMG

increased effector memory T-helper cell number ( J:211773 )

♂

IMPC - CCP-IMG

increased T-helper cell number ( J:211773 )

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♂

IMPC - CCP-IMG

abnormal lymph node morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged lymph nodes ( J:211773 )

♂

IMPC - CCP-IMG

respiratory system

decreased lung elastance ( J:211773 )

♂

IMPC - CCP-IMG

vision/eye

abnormal eye morphology ( J:211773 )

♂

IMPC - CCP-IMG

anophthalmia ( J:211773 )

♂

IMPC - CCP-IMG