All Phenotypes Chaserr<em1Wei> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Chaserr^em1Wei
endonuclease-mediated mutation 1, Weizmann Institute of Science
MGI:6380711

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Chaserr^em1Wei/Chaserr^em1Wei	involves: BALB/c * C57BL/6	MGI:6384258
ht2	Chaserr^em1Wei/Chaserr⁺	involves: BALB/c * C57BL/6	MGI:6384259
cx3	Chaserr^em1Wei/Chaserr⁺ Chd2^em1Wei/Chd2⁺	involves: BALB/c * C57BL/6	MGI:6384261
cx4	Chaserr^em1Wei/Chaserr^em1Wei Chd2^em1Wei/Chd2^em1Wei	involves: BALB/c * C57BL/6	MGI:6384262

Allelic Composition	Chaserr^em1Wei/Chaserr^em1Wei
Genetic Background	involves: BALB/c * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chaserr^em1Wei mutation (0 available); any Chaserr mutation (11 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:281371 )

• no pups are recovered at weaning

Allelic Composition	Chaserr^em1Wei/Chaserr⁺
Genetic Background	involves: BALB/c * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chaserr^em1Wei mutation (0 available); any Chaserr mutation (11 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:281371 )

• mice die between E18.5 and weaning

reproductive system

abnormal female reproductive system physiology ( J:281371 )

• female mice rarely become pregnant

growth/size/body

malocclusion ( J:281371 )

decreased body weight ( J:281371 )

• in female and male mice

postnatal growth retardation ( J:281371 )

skeleton

malocclusion ( J:281371 )

kyphosis ( J:281371 )

adipose tissue

decreased total fat pad weight ( J:281371 )

craniofacial

malocclusion ( J:281371 )

Allelic Composition	Chaserr^em1Wei/Chaserr⁺ Chd2^em1Wei/Chd2⁺
Genetic Background	involves: BALB/c * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chaserr^em1Wei mutation (0 available); any Chaserr mutation (11 available)
Chd2^em1Wei mutation (0 available); any Chd2 mutation (189 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:281371 )

• fewer than expected mice are born

growth/size/body

decreased body weight ( J:281371 )

Allelic Composition	Chaserr^em1Wei/Chaserr^em1Wei Chd2^em1Wei/Chd2^em1Wei
Genetic Background	involves: BALB/c * C57BL/6

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:281371 )

• mice are born in Mendelian ratios and exhibit no phenotype

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