Chd2^em1Wei
Endonuclease-mediated Allele Detail

Summary

• Symbol: Chd2^em1Wei
• Name: chromodomain helicase DNA binding protein 2; endonuclease-mediated mutation 1, Weizmann Institute of Science
• MGI ID: MGI:6380717
• Synonyms: Chd2^m
• Gene: Chd2 Location: Chr7:73076400-73191494 bp, - strand Genetic Position: Chr7, 41.85 cM
• Alliance: Chd2^em1Wei page

Mutation origin

• Strain of Origin: (BALB/c x C57BL/6)F1

Mutation description

• Allele Type: Endonuclease-mediated (Hypomorph)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 3 produced the allele. (J:281371)

Expression

In Mice Carrying this Mutation:	28 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chd2 Mutation: 189 strains or lines available

References

• Original: J:281371 Rom A, et al., Regulation of CHD2 expression by the Chaserr long noncoding RNA gene is essential for viability. Nat Commun. 2019 Nov 8;10(1):5092
• All: 1 reference(s)