All Phenotypes Sdc2<tm1d(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Sdc2^{tm1d(KOMP)Wtsi}
targeted mutation 1d, Wellcome Trust Sanger Institute
MGI:6364847

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sdc2^{tm1d(KOMP)Wtsi}/Sdc2^{tm1d(KOMP)Wtsi}	involves: C57BL/6J * C57BL/6N	MGI:6364850

Allelic Composition	Sdc2^{tm1d(KOMP)Wtsi}/Sdc2^{tm1d(KOMP)Wtsi}
Genetic Background	involves: C57BL/6J * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sdc2^{tm1d(KOMP)Wtsi} mutation (0 available); any Sdc2 mutation (16 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal retina vasculature morphology ( J:276769 )

• reduced postnatal vessel outgrowth

decreased angiogenesis ( J:276769 )

• reduced in the retina

abnormal vascular endothelial cell physiology ( J:276769 )

• reduced migration induced by VEGFA165

decreased vascular endothelial cell proliferation ( J:276769 )

• induced by VEGFA165

homeostasis/metabolism

delayed wound healing ( J:276769 )

• in the skin

vision/eye

abnormal retina vasculature morphology ( J:276769 )

• reduced postnatal vessel outgrowth

cellular

decreased vascular endothelial cell proliferation ( J:276769 )

• induced by VEGFA165

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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