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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cpgi5563tm1.1(NCC)Wcs
targeted mutation 1.1, William C Skarnes
MGI:6359756
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Cpgi5563tm1.1(NCC)Wcs/Cpgi5563tm1.1(NCC)Wcs C57BL/6N-Cpgi5563tm1.1(NCC)Wcs/Wtsi MGI:6359781


Genotype
MGI:6359781
hm1
Allelic
Composition		 Cpgi5563tm1.1(NCC)Wcs/Cpgi5563tm1.1(NCC)Wcs
Genetic
Background		 C57BL/6N-Cpgi5563tm1.1(NCC)Wcs/Wtsi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cpgi5563tm1.1(NCC)Wcs mutation (1 available); any Cpgi5563 mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:277622 )
• some mice die between E14.5 and P14

homeostasis/metabolism
decreased circulating cholesterol level ( J:277622 )
• in female and male mice
decreased circulating triglyceride level ( J:277622 )
• in female and male mice
decreased circulating amylase level ( J:277622 )
• in female and male mice

immune system
decreased gamma-delta T cell number ( J:277622 )
• in female mice
• however, reduced levels in male mice does not reach significance

skeleton

growth/size/body
increased body weight ( J:277622 )
• in female and male mice

hematopoietic system
decreased gamma-delta T cell number ( J:277622 )
• in female mice
• however, reduced levels in male mice does not reach significance




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory