Phenotypes associated with this allele

• Allele Symbol: Epg5^em1(IMPC)H
• Allele Name: endonuclease-mediated mutation 1, Harwell
• Allele ID: MGI:6358076
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Epg5^em1(IMPC)H/Epg5^em1(IMPC)H	C57BL/6NTac-Epg5^em1(IMPC)H/H	MGI:6492824

Genotype
MGI:6492824

hm1

• Allelic Composition: Epg5^em1(IMPC)H/Epg5^em1(IMPC)H
• Genetic Background: C57BL/6NTac-Epg5^em1(IMPC)H/H

Data Sources

IMPC Data for Epg5

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased startle reflex ( J:211773 )

♂

IMPC - HAR

tremors ( J:211773 )

IMPC - HAR

abnormal gait ( J:211773 )

♂

IMPC - HAR

hyperactivity ( J:211773 )

IMPC - HAR

cardiovascular system

increased heart rate ( J:211773 )

♀

IMPC - HAR

growth/size/body

increased spleen weight ( J:211773 )

IMPC - HAR

hematopoietic system

increased spleen weight ( J:211773 )

IMPC - HAR

increased red blood cell distribution width ( J:211773 )

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

IMPC - HAR

increased leukocyte cell number ( J:211773 )

IMPC - HAR

increased basophil cell number ( J:211773 )

♀

IMPC - HAR

increased neutrophil cell number ( J:211773 )

IMPC - HAR

increased lymphocyte cell number ( J:211773 )

♀

IMPC - HAR

increased large unstained cell number ( J:211773 )

♀

IMPC - HAR

increased monocyte cell number ( J:211773 )

IMPC - HAR

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

IMPC - HAR

increased circulating iron level ( J:211773 )

♀

IMPC - HAR

increased circulating alanine transaminase level ( J:211773 )

IMPC - HAR

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - HAR

increased circulating amylase level ( J:211773 )

♀

IMPC - HAR

increased circulating aspartate transaminase level ( J:211773 )

IMPC - HAR

decreased circulating serum albumin level ( J:211773 )

♀

IMPC - HAR

immune system

increased spleen weight ( J:211773 )

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

IMPC - HAR

increased leukocyte cell number ( J:211773 )

IMPC - HAR

increased basophil cell number ( J:211773 )

♀

IMPC - HAR

increased neutrophil cell number ( J:211773 )

IMPC - HAR

increased lymphocyte cell number ( J:211773 )

♀

IMPC - HAR

increased large unstained cell number ( J:211773 )

♀

IMPC - HAR

increased monocyte cell number ( J:211773 )

IMPC - HAR

limbs/digits/tail

short tibia ( J:211773 )

♀

IMPC - HAR

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - HAR

skeleton

short tibia ( J:211773 )

♀

IMPC - HAR

increased bone mineral density ( J:211773 )

♂

IMPC - HAR