All Phenotypes Atg5<em1Smoc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Atg5^em1Smoc
endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI:6358045

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Atg5^em1Smoc/Atg5^em1Smoc S100a4^em1(cre)Zhyg/S100a4⁺	involves: C57BL/6J	MGI:7413887

Allelic Composition	Atg5^em1Smoc/Atg5^em1Smoc S100a4^em1(cre)Zhyg/S100a4⁺
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atg5^em1Smoc mutation (0 available); any Atg5 mutation (29 available)
S100a4^em1(cre)Zhyg mutation (0 available); any S100a4 mutation (23 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

abnormal tumor morphology ( J:330821 )

• reduced collagen in the pancreas of mice implanted with murine pancreatic ductal adenocarcinoma cells

decreased tumor growth/size ( J:330821 )

• due to reduced proliferation compared to when murine pancreatic ductal adenocarcinoma cells are implanted into control mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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