Atg5^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Atg5^em1Smoc
• Name: autophagy related 5; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6358045
• Synonyms: Atg5^{em2(flox)Smoc}
• Gene: Atg5 Location: Chr10:44144354-44240287 bp, + strand Genetic Position: Chr10, 23.24 cM
• Alliance: Atg5^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• LoxP sites were inserted to flank exon 3 via CRISPR/Cas9-mediated genome editing technology. (J:287885)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atg5 Mutation: 27 strains or lines available

References

• Original: J:287885 Du S, et al., Dioscin Alleviates Crystalline Silica-Induced Pulmonary Inflammation and Fibrosis through Promoting Alveolar Macrophage Autophagy. Theranostics. 2019;9(7):1878-1892
• All: 3 reference(s)