Phenotypes associated with this allele

• Allele Symbol: Vim^tm1Sibg
• Allele Name: targeted mutation 1, Shigeyoshi Itohara
• Allele ID: MGI:6355955
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vim^tm1Sibg/Vim^tm1Sibg	C57BL/6-Vim^tm1Sibg	MGI:8401762

Genotype
MGI:8401762

hm1

• Allelic Composition: Vim^tm1Sibg/Vim^tm1Sibg
• Genetic Background: C57BL/6-Vim^tm1Sibg

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

chromosomal instability ( J:276637 )

• binucleation and aneuploidy in lens epithelial cells at age 3 months

vision/eye

lens vacuoles ( J:276637 )

abnormal lens epithelium morphology ( J:276637 )

• fewer cells

disorganized secondary lens fibers ( J:276637 )

• disorganized lens fiber membranes and nuclei at age 4 months

cataract ( J:276637 )

• at age 11 months

microphthalmia ( J:276637 )