All Phenotypes Amelx<em1(IMPC)Ccpcz> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Amelx^{em1(IMPC)Ccpcz}
endonuclease-mediated mutation 1, Institute of Molecular Genetics
MGI:6341952

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Amelx^{em1(IMPC)Ccpcz}/Amelx^{em1(IMPC)Ccpcz}	C57BL/6N-Amelx^{em1(IMPC)Ccpcz}/Ccpcz	MGI:6731245
ht2	Amelx^{em1(IMPC)Ccpcz}/Amelx⁺	C57BL/6N-Amelx^{em1(IMPC)Ccpcz}/Ccpcz	MGI:7471859
ot3	Amelx^{em1(IMPC)Ccpcz}/Y	C57BL/6N-Amelx^{em1(IMPC)Ccpcz}/Ccpcz	MGI:6731244

Allelic Composition	Amelx^{em1(IMPC)Ccpcz}/Amelx^{em1(IMPC)Ccpcz}
Genetic Background	C57BL/6N-Amelx^{em1(IMPC)Ccpcz}/Ccpcz

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amelx^{em1(IMPC)Ccpcz} mutation (0 available); any Amelx mutation (25 available)

Data Sources

IMPC Data for Amelx

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal tooth morphology ( J:211773 )

IMPC - CCP-IMG

abnormal tooth color ( J:211773 )

IMPC - CCP-IMG

absent teeth ( J:211773 )

IMPC - CCP-IMG

digestive/alimentary system

abnormal stomach morphology ( J:211773 )

IMPC - CCP-IMG

enlarged stomach ( J:211773 )

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal thymus morphology ( J:211773 )

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

IMPC - CCP-IMG

growth/size/body

abnormal tooth morphology ( J:211773 )

IMPC - CCP-IMG

abnormal tooth color ( J:211773 )

IMPC - CCP-IMG

absent teeth ( J:211773 )

IMPC - CCP-IMG

decreased body weight ( J:211773 )

IMPC - CCP-IMG

hematopoietic system

abnormal thymus morphology ( J:211773 )

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

IMPC - CCP-IMG

homeostasis/metabolism

decreased circulating alkaline phosphatase level ( J:211773 )

IMPC - CCP-IMG

immune system

abnormal thymus morphology ( J:211773 )

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

IMPC - CCP-IMG

respiratory system

increased lung tissue damping ( J:211773 )

IMPC - CCP-IMG

increased airway resistance ( J:211773 )

IMPC - CCP-IMG

skeleton

abnormal tooth morphology ( J:211773 )

IMPC - CCP-IMG

abnormal tooth color ( J:211773 )

IMPC - CCP-IMG

absent teeth ( J:211773 )

IMPC - CCP-IMG

Allelic Composition	Amelx^{em1(IMPC)Ccpcz}/Amelx⁺
Genetic Background	C57BL/6N-Amelx^{em1(IMPC)Ccpcz}/Ccpcz

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amelx^{em1(IMPC)Ccpcz} mutation (0 available); any Amelx mutation (25 available)

Data Sources

IMPC Data for Amelx

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal tooth morphology ( J:211773 )

IMPC - CCP-IMG

growth/size/body

abnormal tooth morphology ( J:211773 )

IMPC - CCP-IMG

hematopoietic system

increased eosinophil cell number ( J:211773 )

IMPC - CCP-IMG

decreased lymphocyte cell number ( J:211773 )

IMPC - CCP-IMG

immune system

increased eosinophil cell number ( J:211773 )

IMPC - CCP-IMG

decreased lymphocyte cell number ( J:211773 )

IMPC - CCP-IMG

abnormal lymph node morphology ( J:211773 )

IMPC - CCP-IMG

enlarged lymph nodes ( J:211773 )

IMPC - CCP-IMG

respiratory system

increased pulmonary respiratory rate ( J:211773 )

IMPC - CCP-IMG

skeleton

abnormal tooth morphology ( J:211773 )

IMPC - CCP-IMG

abnormal vertebral arch morphology ( J:211773 )

IMPC - CCP-IMG

vertebral transformation ( J:211773 )

IMPC - CCP-IMG

Allelic Composition	Amelx^{em1(IMPC)Ccpcz}/Y
Genetic Background	C57BL/6N-Amelx^{em1(IMPC)Ccpcz}/Ccpcz

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amelx^{em1(IMPC)Ccpcz} mutation (0 available); any Amelx mutation (25 available)

Data Sources

IMPC Data for Amelx

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - CCP-IMG

enlarged heart ( J:211773 )

IMPC - CCP-IMG

craniofacial

abnormal tooth morphology ( J:211773 )

IMPC - CCP-IMG

abnormal tooth color ( J:211773 )

IMPC - CCP-IMG

absent teeth ( J:211773 )

IMPC - CCP-IMG

abnormal zygomatic bone morphology ( J:211773 )

IMPC - CCP-IMG

digestive/alimentary system

abnormal stomach morphology ( J:211773 )

IMPC - CCP-IMG

enlarged stomach ( J:211773 )

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal thymus morphology ( J:211773 )

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

IMPC - CCP-IMG

abnormal seminal vesicle morphology ( J:211773 )

IMPC - CCP-IMG

small seminal vesicle ( J:211773 )

IMPC - CCP-IMG

abnormal testis morphology ( J:211773 )

IMPC - CCP-IMG

small testis ( J:211773 )

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

IMPC - CCP-IMG

abnormal tooth morphology ( J:211773 )

IMPC - CCP-IMG

abnormal tooth color ( J:211773 )

IMPC - CCP-IMG

absent teeth ( J:211773 )

IMPC - CCP-IMG

hematopoietic system

abnormal thymus morphology ( J:211773 )

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

IMPC - CCP-IMG

decreased NK T cell number ( J:211773 )

IMPC - CCP-IMG

decreased CD4-positive NK T cell number ( J:211773 )

IMPC - CCP-IMG

decreased memory-marker CD4-positive NK T cell number ( J:211773 )

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

small spleen ( J:211773 )

IMPC - CCP-IMG

immune system

abnormal thymus morphology ( J:211773 )

IMPC - CCP-IMG

enlarged thymus ( J:211773 )

IMPC - CCP-IMG

decreased NK T cell number ( J:211773 )

IMPC - CCP-IMG

decreased CD4-positive NK T cell number ( J:211773 )

IMPC - CCP-IMG

decreased memory-marker CD4-positive NK T cell number ( J:211773 )

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

IMPC - CCP-IMG

small spleen ( J:211773 )

IMPC - CCP-IMG

integument

abnormal skin morphology ( J:211773 )

IMPC - CCP-IMG

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

IMPC - CCP-IMG

small seminal vesicle ( J:211773 )

IMPC - CCP-IMG

abnormal testis morphology ( J:211773 )

IMPC - CCP-IMG

small testis ( J:211773 )

IMPC - CCP-IMG

skeleton

abnormal tooth morphology ( J:211773 )

IMPC - CCP-IMG

abnormal tooth color ( J:211773 )

IMPC - CCP-IMG

absent teeth ( J:211773 )

IMPC - CCP-IMG

abnormal zygomatic bone morphology ( J:211773 )

IMPC - CCP-IMG

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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