Phenotypes associated with this allele

• Allele Symbol: Fam83h^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:6341855
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fam83h^em1(IMPC)Ccpcz/Fam83h^em1(IMPC)Ccpcz	C57BL/6N-Fam83h^em1(IMPC)Ccpcz/Ccpcz	MGI:6408375
ht2	Fam83h^em1(IMPC)Ccpcz/Fam83h^+	C57BL/6N-Fam83h^em1(IMPC)Ccpcz/Ccpcz	MGI:6461261

Genotype
MGI:6408375

hm1

• Allelic Composition: Fam83h^{em1(IMPC)Ccpcz}/Fam83h^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6N-Fam83h^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Fam83h

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal behavior ( J:211773 )

♂

IMPC - CCP-IMG

decreased exploration in new environment ( J:211773 )

♂

IMPC - CCP-IMG

increased freezing behavior ( J:211773 )

♂

IMPC - CCP-IMG

decreased locomotor activity ( J:211773 )

♂

IMPC - CCP-IMG

no spontaneous movement ( J:211773 )

IMPC - CCP-IMG

cardiovascular system

abnormal heart morphology ( J:211773 )

♀

IMPC - CCP-IMG

small heart ( J:211773 )

♀

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal mammary gland morphology ( J:211773 )

♀

IMPC - CCP-IMG

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

small testis ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number ( J:211773 )

♂

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating potassium level ( J:211773 )

♂

IMPC - CCP-IMG

abnormal cholesterol homeostasis ( J:211773 )

♂

IMPC - CCP-IMG

immune system

increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number ( J:211773 )

♂

IMPC - CCP-IMG

integument

abnormal mammary gland morphology ( J:211773 )

♀

IMPC - CCP-IMG

abnormal coat/ hair morphology ( J:211773 )

♀

IMPC - CCP-IMG

abnormal coat appearance ( J:211773 )

IMPC - CCP-IMG

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

♀

IMPC - CCP-IMG

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - CCP-IMG

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - CCP-IMG

reproductive system

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

small testis ( J:211773 )

♂

IMPC - CCP-IMG

Genotype
MGI:6461261

ht2

• Allelic Composition: Fam83h^{em1(IMPC)Ccpcz}/Fam83h⁺
• Genetic Background: C57BL/6N-Fam83h^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Fam83h

endocrine/exocrine glands

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - CCP-IMG

abnormal gallbladder morphology ( J:211773 )

♂

IMPC - CCP-IMG

liver/biliary system

abnormal gallbladder morphology ( J:211773 )

♂

IMPC - CCP-IMG

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - CCP-IMG