Phenotypes associated with this allele

• Allele Symbol: Maz^em1(IMPC)Ics
• Allele Name: endonuclease-mediated mutation 1, Mouse Clinical Institute
• Allele ID: MGI:6336151
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Maz^em1(IMPC)Ics/Maz^+	C57BL/6N-Maz^em1(IMPC)Ics/Ics	MGI:6408495

Genotype
MGI:6408495

ht1

• Allelic Composition: Maz^em1(IMPC)Ics/Maz⁺
• Genetic Background: C57BL/6N-Maz^em1(IMPC)Ics/Ics

Data Sources

IMPC Data for Maz

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased exploration in new environment ( J:211773 )

♀

IMPC - ICS

growth/size/body

abnormal head morphology ( J:211773 )

♂

IMPC - ICS

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - ICS

nervous system

small lateral ventricles ( J:343325 )

♂ • in adult males, the area of the lateral ventricles is reduced by 37% relative to wild-type males

decreased corpus callosum size ( J:343325 )

♂ • in adult males, the height of the corpus callosum is reduced by 17% relative to wild-type males

decreased brain internal capsule size ( J:343325 )

♂ • in adult males, the area of the internal capsule is reduced by 10% relative to wild-type males

decreased habenula size ( J:343325 )

♂ • in adult males, the area of the habenular nucleus is reduced by 14% relative to wild-type males

decreased cingulate cortex size ( J:343325 )

• in adult males, the height of the cingulate cortex is reduced by 15% relative to wild-type males

• in adult females, the height of the cingulate cortex is reduced by 11% relative to wild-type females

increased secondary somatosensory cortex size ( J:343325 )

♂ • in adult males, the height of the secondary somatosensory cortex at bregma -1.34 mm is increased by 8% relative to wild-type males