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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Bex2tm1Kami
targeted mutation 1, Akihide Kamiya
MGI:6302823
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Bex2tm1Kami/Bex2+ C57BL/6NSlc-Bex2tm1Kami MGI:6478181
ot2
Bex2tm1Kami/Y C57BL/6NSlc-Bex2tm1Kami MGI:6478183


Genotype
MGI:6478181
ht1
Allelic
Composition
Bex2tm1Kami/Bex2+
Genetic
Background
C57BL/6NSlc-Bex2tm1Kami
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bex2tm1Kami mutation (0 available); any Bex2 mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• females are viable, healthy and fertile with no obvious phenotypes under physiological conditions
• proportions of EGFP-positive cells and EGFP-negative cells in the hepatoblast fraction derived from E13.5 fetal livers are nearly equal, suggesting normal cell proliferation; hepatoblasts isolated from either the EGFP-positive or EGFP-negative fraction form colonies at similar levels




Genotype
MGI:6478183
ot2
Allelic
Composition
Bex2tm1Kami/Y
Genetic
Background
C57BL/6NSlc-Bex2tm1Kami
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bex2tm1Kami mutation (0 available); any Bex2 mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• males are viable, healthy and fertile and grow into adulthood with no obvious phenotypes or significant differences in various tissues examined relative to wild-type males
• in an in vitro colony assay, E13.5 fetal livers show normal cell numbers and percentages of hepatoblasts; the colony forming ability of hepatoblasts is normal





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory