Phenotypes associated with this allele

• Allele Symbol: Kcne1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6287371
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kcne1^tm1b(EUCOMM)Hmgu/Kcne1^tm1b(EUCOMM)Hmgu	C57BL/6N-Kcne1^tm1b(EUCOMM)Hmgu/Ics	MGI:6408462

Genotype
MGI:6408462

hm1

• Allelic Composition: Kcne1^{tm1b(EUCOMM)Hmgu}/Kcne1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Kcne1^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0659_5_A11

Data Sources

IMPC Data for Kcne1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

decreased total body fat amount ( J:211773 )

♀

IMPC - ICS

behavior/neurological

abnormal behavior ( J:211773 )

IMPC - ICS

abnormal cued conditioning behavior ( J:211773 )

IMPC - ICS

decreased anxiety-related response ( J:211773 )

IMPC - ICS

decreased thigmotaxis ( J:211773 )

IMPC - ICS

abnormal motor capabilities/coordination/movement ( J:211773 )

♀

IMPC - ICS

impaired righting response ( J:211773 )

♀

IMPC - ICS

abnormal startle reflex ( J:211773 )

IMPC - ICS

decreased startle reflex ( J:211773 )

IMPC - ICS

tremors ( J:211773 )

♀

IMPC - ICS

trunk curl ( J:211773 )

♀

IMPC - ICS

head bobbing ( J:211773 )

IMPC - ICS

abnormal locomotor behavior ( J:211773 )

IMPC - ICS

abnormal gait ( J:211773 )

♂

IMPC - ICS

decreased vertical activity ( J:211773 )

IMPC - ICS

decreased locomotor activity ( J:211773 )

♀

IMPC - ICS

hyperactivity ( J:211773 )

IMPC - ICS

growth/size/body

increased lean body mass ( J:211773 )

IMPC - ICS

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - ICS

hematopoietic system

increased mean corpuscular volume ( J:211773 )

♀

IMPC - ICS

increased neutrophil cell number ( J:211773 )

♀

IMPC - ICS

decreased lymphocyte cell number ( J:211773 )

♀

IMPC - ICS

increased monocyte cell number ( J:211773 )

♀

IMPC - ICS

homeostasis/metabolism

increased circulating alanine transaminase level ( J:211773 )

♀

IMPC - ICS

increased circulating alkaline phosphatase level ( J:211773 )

♂

IMPC - ICS

immune system

increased neutrophil cell number ( J:211773 )

♀

IMPC - ICS

decreased lymphocyte cell number ( J:211773 )

♀

IMPC - ICS

increased monocyte cell number ( J:211773 )

♀

IMPC - ICS

nervous system

decreased prepulse inhibition ( J:211773 )

IMPC - ICS

skeleton

decreased bone mineral content ( J:211773 )

♀

IMPC - ICS

decreased bone mineral density ( J:211773 )

♀

IMPC - ICS