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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nos3M2Btlr
mutation 2, Bruce Beutler
MGI:6284778
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nos3M2Btlr/Nos3M2Btlr C57BL/6J-Nos3M2Btlr MGI:6284780


Genotype
MGI:6284780
hm1
Allelic
Composition		 Nos3M2Btlr/Nos3M2Btlr
Genetic
Background		 C57BL/6J-Nos3M2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nos3M2Btlr mutation (0 available); any Nos3 mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
increased susceptibility to induced colitis ( J:272392 )
• increased sensitivity to dextran sulfate sodium (DSS)-induced colitis at 7 days after DSS treatment

immune system
increased susceptibility to induced colitis ( J:272392 )
• increased sensitivity to dextran sulfate sodium (DSS)-induced colitis at 7 days after DSS treatment




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory