All Phenotypes Npr2<em1(IMPC)H> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Npr2^em1(IMPC)H
endonuclease-mediated mutation 1, Harwell
MGI:6276971

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Npr2^em1(IMPC)H/Npr2^em1(IMPC)H	C57BL/6N-Npr2^em1(IMPC)H/H	MGI:6461484
ht2	Npr2^em1(IMPC)H/Npr2⁺	C57BL/6N-Npr2^em1(IMPC)H/H	MGI:6461483

Allelic Composition	Npr2^em1(IMPC)H/Npr2^em1(IMPC)H
Genetic Background	C57BL/6N-Npr2^em1(IMPC)H/H

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Npr2^em1(IMPC)H mutation (2 available); any Npr2 mutation (63 available)

Data Sources

IMPC Data for Npr2

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

impaired cued conditioning behavior ( J:211773 )

IMPC - HAR

increased freezing behavior ( J:211773 )

IMPC - HAR

limb grasping ( J:211773 )

IMPC - HAR

tremors ( J:211773 )

IMPC - HAR

trunk curl ( J:211773 )

IMPC - HAR

abnormal locomotor behavior ( J:211773 )

IMPC - HAR

abnormal gait ( J:211773 )

IMPC - HAR

craniofacial

abnormal snout morphology ( J:211773 )

IMPC - HAR

growth/size/body

abnormal head morphology ( J:211773 )

IMPC - HAR

abnormal snout morphology ( J:211773 )

IMPC - HAR

abnormal head size ( J:211773 )

IMPC - HAR

homeostasis/metabolism

decreased circulating alkaline phosphatase level ( J:211773 )

IMPC - HAR

limbs/digits/tail

abnormal forelimb morphology ( J:211773 )

IMPC - HAR

abnormal hindlimb morphology ( J:211773 )

IMPC - HAR

abnormal tail morphology ( J:211773 )

IMPC - HAR

abnormal tail length ( J:211773 )

IMPC - HAR

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HAR

Allelic Composition	Npr2^em1(IMPC)H/Npr2⁺
Genetic Background	C57BL/6N-Npr2^em1(IMPC)H/H

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Npr2^em1(IMPC)H mutation (2 available); any Npr2 mutation (63 available)

Data Sources

IMPC Data for Npr2

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased grip strength ( J:211773 )

IMPC - HAR

craniofacial

abnormal snout morphology ( J:211773 )

IMPC - HAR

growth/size/body

abnormal snout morphology ( J:211773 )

IMPC - HAR

limbs/digits/tail

abnormal tail morphology ( J:211773 )

IMPC - HAR

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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