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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Crtac1em1(IMPC)H
endonuclease-mediated mutation 1, Harwell
MGI:6276953
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Crtac1em1(IMPC)H/Crtac1em1(IMPC)H C57BL/6NTac-Crtac1em1(IMPC)H/H MGI:6696698


Genotype
MGI:6696698
hm1
Allelic
Composition
Crtac1em1(IMPC)H/Crtac1em1(IMPC)H
Genetic
Background
C57BL/6NTac-Crtac1em1(IMPC)H/H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crtac1em1(IMPC)H mutation (2 available); any Crtac1 mutation (41 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological

homeostasis/metabolism

neoplasm
N
• 10 days after being tail vein dosed with B16-F0 mouse melanoma cells that have been stably transfected with a vector carrying the Lrrn4cl cDNA (F0_LRN), mice show no significant differences in the number of pulmonary metastatic colonies relative to wild-type controls, suggesting that, in mice, LRRN4CL does not mediate an enhanced metastatic pulmonary colonization phenotype through binding to CRTAC1





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory