All Phenotypes Agtpbp1<tm1.2Ics> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Agtpbp1^tm1.2Ics
targeted mutation 1.2, Mouse Clinical Institute
MGI:6270378

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Agtpbp1^tm1.2Ics/Agtpbp1^tm1.2Ics	involves: 129S2/SvPas * C57BL/6N	MGI:8223451

Allelic Composition	Agtpbp1^tm1.2Ics/Agtpbp1^tm1.2Ics
Genetic Background	involves: 129S2/SvPas * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agtpbp1^tm1.2Ics mutation (0 available); any Agtpbp1 mutation (66 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal microtubule cytoskeleton morphology ( J:263824 )

• microtubules of mouse embryonic fibroblasts (MEFs) show a significant increase in the growing rate, frequency of catastrophes per min, microtubule curvature, and trajectory curvature relative to microtubules of wild-type MEFs, indicating increased microtubule instability

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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