Agtpbp1^tm1.2Ics
Targeted Allele Detail

Summary

• Symbol: Agtpbp1^tm1.2Ics
• Name: ATP/GTP binding protein 1; targeted mutation 1.2, Mouse Clinical Institute
• MGI ID: MGI:6270378
• Synonyms: CCP1-KO
• Gene: Agtpbp1 Location: Chr13:59597348-59705184 bp, - strand
• Alliance: Agtpbp1^tm1.2Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263824
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP was inserted upstream of exon 20, and an FRT site, loxP site, neomycin cassette, FRT site, and loxP site were inserted downstream of exon 21. FLP-mediated recombination removed the neomycin cassette, leaving exons 20-21 floxed. Cre-mediated recombination deleted exons 20 and 21. (J:263824)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Agtpbp1 Mutation: 66 strains or lines available

References

• Original: J:263824 Munoz-Castaneda R, et al., Cytoskeleton stability is essential for the integrity of the cerebellum and its motor- and affective-related behaviors. Sci Rep. 2018 Feb 15;8(1):3072
• All: 5 reference(s)