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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Strapem1Pkda
endonuclease-mediated mutation 1, Pran K Datta
MGI:6257855
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Strapem1Pkda/Strap+ involves: C57BL/6 MGI:6257857


Genotype
MGI:6257857
ht1
Allelic
Composition		 Strapem1Pkda/Strap+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Strapem1Pkda mutation (0 available); any Strap mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased incidence of tumors by chemical induction ( J:245661 )
• mice treated with the carcinogen AOM and the inflammatory agent DSS show reduced tumor growth in the colon with decreased proliferation in colon tumors

homeostasis/metabolism
decreased incidence of tumors by chemical induction ( J:245661 )
• mice treated with the carcinogen AOM and the inflammatory agent DSS show reduced tumor growth in the colon with decreased proliferation in colon tumors




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory