Strap^em1Pkda
Endonuclease-mediated Allele Detail

Summary

• Symbol: Strap^em1Pkda
• Name: serine/threonine kinase receptor associated protein; endonuclease-mediated mutation 1, Pran K Datta
• MGI ID: MGI:6257855
• Synonyms: Strap^-
• Gene: Strap Location: Chr6:137712080-137728928 bp, + strand Genetic Position: Chr6, 67.27 cM
• Alliance: Strap^em1Pkda page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• Zinc finger technology was used to excise exons 3 and 4. (J:245661)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Strap Mutation: 18 strains or lines available

References

• Original: J:245661 Jin L, et al., STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017 Oct 15;77(20):5464-5478
• All: 3 reference(s)