Phenotypes associated with this allele

• Allele Symbol: Isyna1^em1(IMPC)Bay
• Allele Name: endonuclease-mediated mutation 1, Baylor College of Medicine
• Allele ID: MGI:6257466
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Isyna1^em1(IMPC)Bay/Isyna1^em1(IMPC)Bay	C57BL/6N-Isyna1^em1(IMPC)Bay/BayMmucd	MGI:6480484
ht2	Isyna1^em1(IMPC)Bay/Isyna1^+	C57BL/6N-Isyna1^em1(IMPC)Bay/BayMmucd	MGI:6696784

Genotype
MGI:6480484

hm1

• Allelic Composition: Isyna1^em1(IMPC)Bay/Isyna1^em1(IMPC)Bay
• Genetic Background: C57BL/6N-Isyna1^em1(IMPC)Bay/BayMmucd

Data Sources

IMPC Data for Isyna1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - BCM

abnormal heart looping ( J:211773 )

♂

IMPC - BCM

craniofacial

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - BCM

embryo

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - BCM

abnormal embryo turning ( J:211773 )

IMPC - BCM

abnormal neural tube closure ( J:211773 )

♂

IMPC - BCM

abnormal somite shape ( J:211773 )

♂

IMPC - BCM

abnormal tail bud morphology ( J:211773 )

IMPC - BCM

abnormal visceral yolk sac morphology ( J:211773 )

IMPC - BCM

pale yolk sac ( J:211773 )

♂

IMPC - BCM

limbs/digits/tail

abnormal limb morphology ( J:211773 )

♂

IMPC - BCM

syndactyly ( J:211773 )

♂

IMPC - BCM

abnormal tail morphology ( J:211773 )

♂

IMPC - BCM

abnormal tail bud morphology ( J:211773 )

IMPC - BCM

mortality/aging

prenatal lethality ( J:211773 )

IMPC - BCM

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - BCM

nervous system

abnormal neural tube closure ( J:211773 )

♂

IMPC - BCM

Genotype
MGI:6696784

ht2

• Allelic Composition: Isyna1^em1(IMPC)Bay/Isyna1⁺
• Genetic Background: C57BL/6N-Isyna1^em1(IMPC)Bay/BayMmucd

Data Sources

IMPC Data for Isyna1

cardiovascular system

increased heart rate ( J:211773 )

♂

IMPC - BCM