immune system
• when infected intranasally with Influenza A virus (IAV X-31), mice exhibit increased weight loss (12% at day 6 p.i. vs 5% in wild-type), at least 10-fold higher virus titres at all days tested, and faster penetration of virus in distal bronchioles and alveoli at day 1 p.i. (where not found in wild-type)
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• when infected intranasally with Influenza A virus (IAV X-31)
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mortality/aging
• when infected intranasally with Influenza A virus (IAV X-31)
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