All Phenotypes Lrg1<tm1.1Tnaka> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lrg1^tm1.1Tnaka
targeted mutation 1.1, Tetsuji Naka
MGI:6196322

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lrg1^tm1.1Tnaka/Lrg1^tm1.1Tnaka	involves: C57BL/6J * CBA	MGI:6196331

Allelic Composition	Lrg1^tm1.1Tnaka/Lrg1^tm1.1Tnaka
Genetic Background	involves: C57BL/6J * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrg1^tm1.1Tnaka mutation (0 available); any Lrg1 mutation (14 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased tumor growth/size ( J:263152 )

• of LCC tumor cells injected sub-cutaneously

• however, treatment with a Tgfbr1 inhibitor (SB431542) rescues the phenotype

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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