Lrg1^tm1.1Tnaka
Targeted Allele Detail

Summary

• Symbol: Lrg1^tm1.1Tnaka
• Name: leucine-rich alpha-2-glycoprotein 1; targeted mutation 1.1, Tetsuji Naka
• MGI ID: MGI:6196322
• Gene: Lrg1 Location: Chr17:56426678-56428946 bp, - strand Genetic Position: Chr17, 29.17 cM, cytoband D
• Alliance: Lrg1^tm1.1Tnaka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:263152
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was flanked by loxP sites and followed by an FRT-flanked neomycin resistance cassette. Cre-mediated recombination removed exon 2. (J:263152)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrg1 Mutation: 14 strains or lines available

References

• Original: J:263152 Takemoto N, et al., Leucine-rich alpha-2-glycoprotein promotes TGFbeta1-mediated growth suppression in the Lewis lung carcinoma cell lines. Oncotarget. 2015 May 10;6(13):11009-22
• All: 2 reference(s)