Phenotypes associated with this allele

• Allele Symbol: Tnip1^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6195689
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tnip1^tm1b(EUCOMM)Hmgu/Tnip1^tm1b(EUCOMM)Hmgu	C57BL/6N-Tnip1^tm1b(EUCOMM)Hmgu/H	MGI:6288787

Genotype
MGI:6288787

hm1

• Allelic Composition: Tnip1^{tm1b(EUCOMM)Hmgu}/Tnip1^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Tnip1^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0510_7_F09

Data Sources

IMPC Data for Tnip1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased freezing behavior ( J:211773 )

♀

IMPC - HAR

cardiovascular system

prolonged RR interval ( J:211773 )

♂

IMPC - HAR

growth/size/body

increased spleen weight ( J:211773 )

IMPC - HAR

hematopoietic system

increased spleen weight ( J:211773 )

IMPC - HAR

increased basophil cell number ( J:211773 )

♀

IMPC - HAR

decreased erythrocyte cell number ( J:211773 )

IMPC - HAR

decreased hematocrit ( J:211773 )

IMPC - HAR

decreased hemoglobin content ( J:211773 )

IMPC - HAR

increased mean corpuscular hemoglobin ( J:211773 )

♂

IMPC - HAR

increased mean corpuscular hemoglobin concentration ( J:211773 )

♂

IMPC - HAR

increased red blood cell distribution width ( J:211773 )

IMPC - HAR

thrombocytopenia ( J:211773 )

IMPC - HAR

increased mean platelet volume ( J:211773 )

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♀

IMPC - HAR

increased large unstained cell number ( J:211773 )

♀

IMPC - HAR

increased monocyte cell number ( J:211773 )

IMPC - HAR

homeostasis/metabolism

decreased circulating fructosamine level ( J:211773 )

IMPC - HAR

decreased circulating glucose level ( J:211773 )

♀

IMPC - HAR

decreased circulating cholesterol level ( J:211773 )

IMPC - HAR

decreased circulating HDL cholesterol level ( J:211773 )

IMPC - HAR

decreased circulating triglyceride level ( J:211773 )

♂

IMPC - HAR

decreased circulating iron level ( J:211773 )

♀

IMPC - HAR

increased circulating potassium level ( J:211773 )

♀

IMPC - HAR

increased circulating alanine transaminase level ( J:211773 )

IMPC - HAR

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - HAR

increased circulating aspartate transaminase level ( J:211773 )

IMPC - HAR

decreased circulating serum albumin level ( J:211773 )

IMPC - HAR

immune system

increased spleen weight ( J:211773 )

IMPC - HAR

increased basophil cell number ( J:211773 )

♀

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♀

IMPC - HAR

increased large unstained cell number ( J:211773 )

♀

IMPC - HAR

increased monocyte cell number ( J:211773 )

IMPC - HAR