All Phenotypes Lima1<tm1Blsg> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lima1^tm1Blsg
targeted mutation 1, Bao-Liang Song
MGI:6192724

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Lima1^tm1Blsg/Lima1^tm1Blsg Tg(Vil1-cre/ERT2)23Syr/0	involves: C57BL/6 * DBA/2	MGI:6192734
cn2	Lima1^tm1Blsg/Lima1⁺ Tg(Vil1-cre/ERT2)23Syr/0	involves: C57BL/6 * DBA/2	MGI:6192735

Allelic Composition	Lima1^tm1Blsg/Lima1^tm1Blsg Tg(Vil1-cre/ERT2)23Syr/0
Genetic Background	involves: C57BL/6 * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lima1^tm1Blsg mutation (0 available); any Lima1 mutation (83 available)
Tg(Vil1-cre/ERT2)23Syr mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:263730 )

N	• plasma and liver triglyceride levels are normal when mice are fed a high-fat diet or regular chow

decreased intestinal cholesterol absorption ( J:263730 )

decreased circulating cholesterol level ( J:263730 )

• in mice fed a high-fat diet

decreased circulating HDL cholesterol level ( J:263730 )

• in mice fed a high-fat diet

decreased circulating LDL cholesterol level ( J:263730 )

• in mice fed a high-fat diet

decreased circulating VLDL cholesterol level ( J:263730 )

• in mice fed a high-fat diet

decreased liver cholesterol level ( J:263730 )

• in mice fed a high-fat diet

digestive/alimentary system

decreased intestinal cholesterol absorption ( J:263730 )

liver/biliary system

decreased liver cholesterol level ( J:263730 )

• in mice fed a high-fat diet

Allelic Composition	Lima1^tm1Blsg/Lima1⁺ Tg(Vil1-cre/ERT2)23Syr/0
Genetic Background	involves: C57BL/6 * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lima1^tm1Blsg mutation (0 available); any Lima1 mutation (83 available)
Tg(Vil1-cre/ERT2)23Syr mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

digestive/alimentary system

decreased intestinal cholesterol absorption ( J:263730 )

homeostasis/metabolism

decreased intestinal cholesterol absorption ( J:263730 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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