All Phenotypes Mecp2<em1Dkatz> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mecp2^em1Dkatz
endonuclease-mediated mutation 1, David Katz
MGI:6158911

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Mecp2^em1Dkatz/Mecp2⁺ Tyr^c-ch/Tyr^c-ch	FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J	MGI:6159334
cx2	Mecp2^em1Dkatz/Mecp2^em1Dkatz Tyr^c-ch/Tyr^c-ch	FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J	MGI:6159335
cx3	Mecp2^em1Dkatz/Y Tyr^c-ch/Tyr^c-ch	FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J	MGI:6159336

Allelic Composition	Mecp2^em1Dkatz/Mecp2⁺ Tyr^c-ch/Tyr^c-ch
Genetic Background	FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2^em1Dkatz mutation (0 available); any Mecp2 mutation (45 available)
Tyr^c-ch mutation (79 available); any Tyr mutation (382 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal locomotor behavior ( J:101977 )

• females exhibit a locomotor phenotype onset as early as 14 weeks of age

reproductive system

reproductive system phenotype ( J:101977 )

N	• fertility is normal

Allelic Composition	Mecp2^em1Dkatz/Mecp2^em1Dkatz Tyr^c-ch/Tyr^c-ch
Genetic Background	FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

female infertility ( J:101977 )

Allelic Composition	Mecp2^em1Dkatz/Y Tyr^c-ch/Tyr^c-ch
Genetic Background	FVB.Cg-Pde6b⁺ Tyr^c-ch Mecp2^em1Dkatz/J

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:101977 )

• males die by 10 weeks of age

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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