Phenotypes associated with this allele

• Allele Symbol: Notum^em1(IMPC)Tcp
• Allele Name: endonuclease-mediated mutation 1, The Centre for Phenogenomics
• Allele ID: MGI:6156499
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Notum^em1(IMPC)Tcp/Notum^em1(IMPC)Tcp	C57BL/6NCrl-Notum^em1(IMPC)Tcp/Tcp	MGI:6263038
ht2	Notum^em1(IMPC)Tcp/Notum^+	C57BL/6NCrl-Notum^em1(IMPC)Tcp/Tcp	MGI:6263037

Genotype
MGI:6263038

hm1

• Allelic Composition: Notum^em1(IMPC)Tcp/Notum^em1(IMPC)Tcp
• Genetic Background: C57BL/6NCrl-Notum^em1(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Notum

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - TCP

nervous system

abnormal brain morphology ( J:211773 )

♂

IMPC - TCP

renal/urinary system

abnormal kidney morphology ( J:211773 )

♂

IMPC - TCP

vision/eye

anophthalmia ( J:211773 )

IMPC - TCP

Genotype
MGI:6263037

ht2

• Allelic Composition: Notum^em1(IMPC)Tcp/Notum⁺
• Genetic Background: C57BL/6NCrl-Notum^em1(IMPC)Tcp/Tcp

Data Sources

IMPC Data for Notum

behavior/neurological

decreased exploration in new environment ( J:211773 )

♂

IMPC - TCP

decreased grip strength ( J:211773 )

♀

IMPC - TCP

endocrine/exocrine glands

small ovary ( J:211773 )

♀

IMPC - TCP

hematopoietic system

small spleen ( J:211773 )

♀

IMPC - TCP

homeostasis/metabolism

abnormal cholesterol homeostasis ( J:211773 )

IMPC - TCP

immune system

small spleen ( J:211773 )

♀

IMPC - TCP

reproductive system

small ovary ( J:211773 )

♀

IMPC - TCP

abnormal uterus morphology ( J:211773 )

♀

IMPC - TCP

small uterus ( J:211773 )

♀

IMPC - TCP