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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Psmc5tm1.1Itl
targeted mutation 1.1, inGenious Targeting Laboratory
MGI:6155608
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Psmc5tm1.1Itl/Psmc5tm1.1Itl involves: 129S6/SvEvTac * C57BL/6NTac MGI:6155609


Genotype
MGI:6155609
hm1
Allelic
Composition
Psmc5tm1.1Itl/Psmc5tm1.1Itl
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Psmc5tm1.1Itl mutation (0 available); any Psmc5 mutation (31 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• upon multiple sessions, cocaine-exposed mice fail to exhibit an increase in locomotor activity unlike wild-type mice
• however, mice exhibit normal habituation and acute response to cocaine exposure
• upon multiple sessions, cocaine-exposed mice fail to exhibit an increase in locomotor activity unlike wild-type mice
• however, mice exhibit normal habituation and acute response to cocaine exposure





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory