About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Coro1ctm1c(KOMP)Wtsi
targeted mutation 1c, Wellcome Trust Sanger Institute
MGI:6151181
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Coro1ctm1c(KOMP)Wtsi/Coro1ctm1c(KOMP)Wtsi
Ptentm2Mak/Ptentm2Mak
Trp53tm1Brn/Trp53tm1Brn
Tg(GFAP-cre/Esr1*,-lacZ)ASbk/0 		involves: 129P2/OlaHsd * C57BL/6N * FVB/NJ MGI:6444814


Genotype
MGI:6444814
cn1
Allelic
Composition		 Coro1ctm1c(KOMP)Wtsi/Coro1ctm1c(KOMP)Wtsi
Ptentm2Mak/Ptentm2Mak
Trp53tm1Brn/Trp53tm1Brn
Tg(GFAP-cre/Esr1*,-lacZ)ASbk/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6N * FVB/NJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Coro1ctm1c(KOMP)Wtsi mutation (0 available); any Coro1c mutation (69 available)
Ptentm2Mak mutation (4 available); any Pten mutation (86 available)
Tg(GFAP-cre/Esr1*,-lacZ)ASbk mutation (1 available)
Trp53tm1Brn mutation (20 available); any Trp53 mutation (238 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:290447 )
• as in mice with wild-type Coro1c in tamoxifen-treated mice

neoplasm
increased glioblastoma incidence ( J:290447 )
• as in mice with wild-type Coro1c in tamoxifen-treated mice

nervous system
increased glioblastoma incidence ( J:290447 )
• as in mice with wild-type Coro1c in tamoxifen-treated mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory