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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gpr37l1tm1d(EUCOMM)Wtsi
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:6150820
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Gpr37l1tm1d(EUCOMM)Wtsi/Gpr37l1tm1d(EUCOMM)Wtsi involves: BALB/cJ * C57BL/6N * SJL MGI:6151045
ht2
Gpr37l1tm1d(EUCOMM)Wtsi/Gpr37l1+ involves: BALB/cJ * C57BL/6N * SJL MGI:6151046


Genotype
MGI:6151045
hm1
Allelic
Composition
Gpr37l1tm1d(EUCOMM)Wtsi/Gpr37l1tm1d(EUCOMM)Wtsi
Genetic
Background
involves: BALB/cJ * C57BL/6N * SJL
Cell Lines EPD0486_2_B09
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpr37l1tm1d(EUCOMM)Wtsi mutation (1 available); any Gpr37l1 mutation (32 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
N
• anesthetized female mice exhibit normal left ventricular systolic pressure, end-diastolic pressure and dP/dT max or min
• in anesthetized female mice
• in anesthetized female mice
• in female mice whether anesthetized or conscious
• in female mice whether anesthetized or conscious

homeostasis/metabolism
• female and male mice exhibit protection from AngII-induced cardiac fibrosis compared with wild-type mice
• male mice exhibit increased AngII-induced left ventricular hypertrophy and pulmonary edema resulting from congestive heart failure compared with wild-type mice
• however, female mice exhibit AngII-induced hypertension




Genotype
MGI:6151046
ht2
Allelic
Composition
Gpr37l1tm1d(EUCOMM)Wtsi/Gpr37l1+
Genetic
Background
involves: BALB/cJ * C57BL/6N * SJL
Cell Lines EPD0486_2_B09
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpr37l1tm1d(EUCOMM)Wtsi mutation (1 available); any Gpr37l1 mutation (32 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system





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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory