Phenotypes associated with this allele

• Allele Symbol: Syncrip^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6120727
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Syncrip^tm1b(EUCOMM)Hmgu/Syncrip^tm1b(EUCOMM)Hmgu	C57BL/6N-Syncrip^tm1b(EUCOMM)Hmgu/Ieg	MGI:7267100
ht2	Syncrip^tm1b(EUCOMM)Hmgu/Syncrip^+	C57BL/6N-Syncrip^tm1b(EUCOMM)Hmgu/Ieg	MGI:6696927

Genotype
MGI:7267100

hm1

• Allelic Composition: Syncrip^{tm1b(EUCOMM)Hmgu}/Syncrip^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Syncrip^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0723_2_B10

Data Sources

IMPC Data for Syncrip

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HMGU

Genotype
MGI:6696927

ht2

• Allelic Composition: Syncrip^{tm1b(EUCOMM)Hmgu}/Syncrip⁺
• Genetic Background: C57BL/6N-Syncrip^{tm1b(EUCOMM)Hmgu}/Ieg
• Cell Lines: HEPD0723_2_B10

Data Sources

IMPC Data for Syncrip

behavior/neurological

abnormal behavior ( J:211773 )

IMPC - HMGU

decreased anxiety-related response ( J:211773 )

IMPC - HMGU

decreased thigmotaxis ( J:211773 )

IMPC - HMGU

increased startle reflex ( J:211773 )

IMPC - HMGU

increased grip strength ( J:211773 )

♀

IMPC - HMGU

hyperactivity ( J:211773 )

IMPC - HMGU

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - HMGU

hematopoietic system

decreased mean platelet volume ( J:211773 )

IMPC - HMGU

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - HMGU

impaired glucose tolerance ( J:211773 )

IMPC - HMGU