mortality/aging
• although normal looking blastocysts are present at relatively normal Mendelian ratios at E3.5, no embryos or excess resorption sites are observed at E7.5
• however, blastocysts hatch from the zona pellucida and form normal outgrowth colonies with apparent inner cell mass (ICM), trophectoderm (TE), and primitive endoderm (PrE) cells after 3 days in culture
|