Phenotypes associated with this allele

• Allele Symbol: Kat14^{tm1d(KOMP)Wtsi}
• Allele Name: targeted mutation 1d, Wellcome Trust Sanger Institute
• Allele ID: MGI:5910764
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	\Kat14^tm1d(KOMP)Wtsi/\Kat14^+	D2.B6N(Cg)-Kat14^tm1d(KOMP)Wtsi	MGI:5912194
cx2	\Kat14^tm1d(KOMP)Wtsi/\Ppcd1	D2.Cg-Kat14^tm1d(KOMP)Wtsi/Ppcd1	MGI:5912185
cx3	\Dzank1^tm1a(KOMP)Wtsi/\Dzank1^+ \Kat14^tm1d(KOMP)Wtsi/\Kat14^+	involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6N * DBA/2J	MGI:5912196

Genotype
MGI:5912194

ht1

• Allelic Composition: \Kat14^{tm1d(KOMP)Wtsi}/\Kat14⁺
• Genetic Background: D2.B6N(Cg)-Kat14^{tm1d(KOMP)Wtsi}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

vision/eye phenotype ( J:236024 )

N • unlike Ppcd1 heterozygotes, mice does not exhibit epithelized corneal endothelium at 3 or 8 months of age or enlarged eyes at 8 months of age

Genotype
MGI:5912185

cx2

• Allelic Composition: \Kat14^{tm1d(KOMP)Wtsi}/\Ppcd1
• Genetic Background: D2.Cg-Kat14^{tm1d(KOMP)Wtsi}/Ppcd1

mortality/aging

preweaning lethality, complete penetrance ( J:236024 )

• no mice are present when survival is scored at weaning

Genotype
MGI:5912196

cx3

• Allelic Composition: \Dzank1^{tm1a(KOMP)Wtsi}/\Dzank1⁺; \Kat14^{tm1d(KOMP)Wtsi}/\Kat14⁺
• Genetic Background: involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6N * DBA/2J

vision/eye

vision/eye phenotype ( J:236024 )

N • unlike Ppcd1 heterozygotes, mice does not exhibit enlarged eyes at 4 to 5 months