Phenotypes associated with this allele

• Allele Symbol: Utp4^em1(IMPC)J
• Allele Name: endonuclease-mediated mutation 1, Jackson
• Allele ID: MGI:5907896
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Utp4^em1(IMPC)J/Utp4^em1(IMPC)J	C57BL/6NJ-Utp4^em1(IMPC)J/Mmjax	MGI:6263845
ht2	Utp4^em1(IMPC)J/Utp4^+	C57BL/6NJ-Utp4^em1(IMPC)J/Mmjax	MGI:6263844

Genotype
MGI:6263845

hm1

• Allelic Composition: Utp4^em1(IMPC)J/Utp4^em1(IMPC)J
• Genetic Background: C57BL/6NJ-Utp4^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for Utp4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6263844

ht2

• Allelic Composition: Utp4^em1(IMPC)J/Utp4⁺
• Genetic Background: C57BL/6NJ-Utp4^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for Utp4

behavior/neurological

impaired righting response ( J:211773 )

IMPC - JAX

limb grasping ( J:211773 )

IMPC - JAX

embryo

abnormal neural tube closure ( J:211773 )

IMPC - JAX

hematopoietic system

increased leukocyte cell number ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

♀

IMPC - JAX

immune system

increased leukocyte cell number ( J:211773 )

♂

IMPC - JAX

integument

abnormal coat/ hair morphology ( J:211773 )

IMPC - JAX

absent vibrissae ( J:211773 )

♂

IMPC - JAX

nervous system

abnormal neural tube closure ( J:211773 )

IMPC - JAX