Phenotypes associated with this allele

• Allele Symbol: Zfp407^em1(IMPC)J
• Allele Name: endonuclease-mediated mutation 1, Jackson
• Allele ID: MGI:5907859
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zfp407^em1(IMPC)J/Zfp407^em1(IMPC)J	C57BL/6NJ-Zfp407^em1(IMPC)J/Mmjax	MGI:6263914
ht2	Zfp407^em1(IMPC)J/Zfp407^+	C57BL/6NJ-Zfp407^em1(IMPC)J/Mmjax	MGI:6263913

Genotype
MGI:6263914

hm1

• Allelic Composition: Zfp407^em1(IMPC)J/Zfp407^em1(IMPC)J
• Genetic Background: C57BL/6NJ-Zfp407^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for Zfp407

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

failure of blastocyst formation ( J:279207 )

• stalled cleavage stage embryos recovered at E3.5 show no further development in culture

failure of blastocyst to hatch from the zona pellucida ( J:279207 )

• stalled cleavage stage embryos recovered at E3.5 fail to hatch from the zona pellucida after 3 days in culture

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

embryonic lethality before implantation, complete penetrance ( J:279207 )

• homozygous embryos are present at expected Mendelian ratios at E3.5 but arrest prior to blastocyst formation; no embryos are recovered at E7.5

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6263913

ht2

• Allelic Composition: Zfp407^em1(IMPC)J/Zfp407⁺
• Genetic Background: C57BL/6NJ-Zfp407^em1(IMPC)J/Mmjax

Data Sources

IMPC Data for Zfp407

behavior/neurological

hyperactivity ( J:211773 )

IMPC - JAX

increased vertical activity ( J:211773 )

♂

IMPC - JAX