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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Piezo1tm1c(KOMP)Wtsi
targeted mutation 1c, Wellcome Trust Sanger Institute
MGI:5823989
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Piezo1tm1c(KOMP)Wtsi/Piezo1tm1c(KOMP)Wtsi
Tg(Tek-cre)12Flv/0 		involves: C57BL/6J * C57BL/6N MGI:5824010


Genotype
MGI:5824010
cn1
Allelic
Composition		 Piezo1tm1c(KOMP)Wtsi/Piezo1tm1c(KOMP)Wtsi
Tg(Tek-cre)12Flv/0
Genetic
Background		 involves: C57BL/6J * C57BL/6N
Cell Lines EPD0500_5_F12
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Piezo1tm1c(KOMP)Wtsi mutation (1 available); any Piezo1 mutation (87 available)
Tg(Tek-cre)12Flv mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
embryonic growth retardation ( J:217082 )
• embryos exhibit growth retardation at E10.5

embryo
abnormal vitelline vasculature morphology ( J:217082 )
• at E9.5 and E10.5, embryos exhibit disrupted yolk sac vasculature development
embryonic growth retardation ( J:217082 )
• embryos exhibit growth retardation at E10.5

cardiovascular system
abnormal vitelline vasculature morphology ( J:217082 )
• at E9.5 and E10.5, embryos exhibit disrupted yolk sac vasculature development




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory