About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Piezo1tm1c(KOMP)Wtsi
targeted mutation 1c, Wellcome Trust Sanger Institute
MGI:5823989
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Piezo1tm1c(KOMP)Wtsi/Piezo1tm1c(KOMP)Wtsi
Tg(Tek-cre)12Flv/0 		involves: C57BL/6J * C57BL/6N MGI:5824010


Genotype
MGI:5824010
cn1
Allelic
Composition		 Piezo1tm1c(KOMP)Wtsi/Piezo1tm1c(KOMP)Wtsi
Tg(Tek-cre)12Flv/0
Genetic
Background		 involves: C57BL/6J * C57BL/6N
Cell Lines EPD0500_5_F12
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Piezo1tm1c(KOMP)Wtsi mutation (1 available); any Piezo1 mutation (88 available)
Tg(Tek-cre)12Flv mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
embryonic growth retardation ( J:217082 )
• embryos exhibit growth retardation at E10.5

embryo
abnormal vitelline vasculature morphology ( J:217082 )
• at E9.5 and E10.5, embryos exhibit disrupted yolk sac vasculature development
embryonic growth retardation ( J:217082 )
• embryos exhibit growth retardation at E10.5

cardiovascular system
abnormal vitelline vasculature morphology ( J:217082 )
• at E9.5 and E10.5, embryos exhibit disrupted yolk sac vasculature development




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory