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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tyrem4Ove
endonuclease-mediated mutation 4, Paul Overbeek
MGI:5817601
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		a/a
Tyrem4Ove/Tyrem4Ove 		involves: C57BL/6 * FVB MGI:5817604
cx2
 		a/a
Tyrc/Tyrem4Ove 		involves: C57BL/6 * FVB MGI:5817616


Genotype
MGI:5817604
cx1
Allelic
Composition		 a/a
Tyrem4Ove/Tyrem4Ove
Genetic
Background		 involves: C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (166 available); any a mutation (468 available)
Tyrem4Ove mutation (1 available); any Tyr mutation (382 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
diluted coat color ( J:94077 )
• the fur of these mice appears dark gray

limbs/digits/tail

pigmentation
diluted coat color ( J:94077 )
• the fur of these mice appears dark gray
abnormal eye pigmentation ( J:94077 )
• the eyes of these mice exhibit altered pigmentation

vision/eye
abnormal eye pigmentation ( J:94077 )
• the eyes of these mice exhibit altered pigmentation




Genotype
MGI:5817616
cx2
Allelic
Composition		 a/a
Tyrc/Tyrem4Ove
Genetic
Background		 involves: C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (166 available); any a mutation (468 available)
Tyrc mutation (79 available); any Tyr mutation (382 available)
Tyrem4Ove mutation (1 available); any Tyr mutation (382 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
diluted coat color ( J:94077 )
• the fur of these mice appears medium gray

pigmentation
diluted coat color ( J:94077 )
• the fur of these mice appears medium gray
abnormal eye pigmentation ( J:94077 )
• the eyes of these mice exhibit altered pigmentation

vision/eye
abnormal eye pigmentation ( J:94077 )
• the eyes of these mice exhibit altered pigmentation




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory