Analysis Tools
nervous system
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• at E13.5 and E15.5
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Allele Symbol Allele Name Allele ID |
Rcor2tm1c(EUCOMM)Wtsi targeted mutation 1c, Wellcome Trust Sanger Institute MGI:5806455 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at E13.5 and E15.5
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at E13.5 and E15.5
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• abnormalities in lamination at E15.5
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• expression analysis indicates a dramatic decrease at E15.5
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• at E15.5
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• at E15.5
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• cortical neural progenitor cells appear to exit the cell cycle earlier compared to controls
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• cortical neural progenitor cells form smaller neurospheres in culture
• inhibition of SHH with Cyclopamine increases neurosphere size
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• cortical neural progenitor cells appear to exit the cell cycle earlier compared to controls
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• cortical neural progenitor cells form smaller neurospheres in culture
• inhibition of SHH with Cyclopamine increases neurosphere size
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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