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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Cnot3tm1.2Tya
targeted mutation 1.2, Tadashi Yamamoto
MGI:5804097
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Cnot3tm1.2Tya/Cnot3tm1.2Tya
Imp3tm1Tya/Imp3tm1Tya
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ 		involves: 129 * 129P2/OlaHsd * C57BL/6 * C57BL/6J * DBA MGI:8261282


Genotype
MGI:8261282
cn1
Allelic
Composition		 Cnot3tm1.2Tya/Cnot3tm1.2Tya
Imp3tm1Tya/Imp3tm1Tya
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic
Background		 involves: 129 * 129P2/OlaHsd * C57BL/6 * C57BL/6J * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cnot3tm1.2Tya mutation (0 available); any Cnot3 mutation (34 available)
Imp3tm1Tya mutation (0 available); any Imp3 mutation (4 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation (6 available); any Speer6-ps1 mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:374252 )

liver/biliary system
abnormal liver sinusoid morphology ( J:374252 )
• misaligned sinusoids

immune system

cardiovascular system
abnormal liver sinusoid morphology ( J:374252 )
• misaligned sinusoids




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory