Phenotypes associated with this allele

• Allele Symbol: Sun1^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5793071
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sun1^tm1b(EUCOMM)Wtsi/Sun1^tm1b(EUCOMM)Wtsi	C57BL/6N-Sun1^tm1b(EUCOMM)Wtsi/Orl	MGI:6263611

Genotype
MGI:6263611

hm1

• Allelic Composition: Sun1^{tm1b(EUCOMM)Wtsi}/Sun1^{tm1b(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Sun1^{tm1b(EUCOMM)Wtsi}/Orl
• Cell Lines: EPD0325_5_F03

Data Sources

IMPC Data for Sun1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

♀

IMPC - ICS

behavior/neurological

abnormal startle reflex ( J:211773 )

♂

IMPC - ICS

decreased startle reflex ( J:211773 )

♂

IMPC - ICS

decreased locomotor activity ( J:211773 )

♀

IMPC - ICS

cardiovascular system

increased heart rate ( J:211773 )

♂

IMPC - ICS

endocrine/exocrine glands

small testis ( J:211773 )

♂

IMPC - ICS

growth/size/body

decreased lean body mass ( J:211773 )

♀

IMPC - ICS

hearing/vestibular/ear

abnormal auditory brainstem response ( J:211773 )

IMPC - ICS

hematopoietic system

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - ICS

increased leukocyte cell number ( J:211773 )

♀

IMPC - ICS

increased neutrophil cell number ( J:211773 )

♂

IMPC - ICS

increased lymphocyte cell number ( J:211773 )

♀

IMPC - ICS

increased monocyte cell number ( J:211773 )

IMPC - ICS

homeostasis/metabolism

increased circulating phosphate level ( J:211773 )

♂

IMPC - ICS

decreased circulating serum albumin level ( J:211773 )

♂

IMPC - ICS

decreased circulating total protein level ( J:211773 )

♂

IMPC - ICS

immune system

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - ICS

increased leukocyte cell number ( J:211773 )

♀

IMPC - ICS

increased neutrophil cell number ( J:211773 )

♂

IMPC - ICS

increased lymphocyte cell number ( J:211773 )

♀

IMPC - ICS

increased monocyte cell number ( J:211773 )

IMPC - ICS

nervous system

small superior vagus ganglion ( J:211773 )

♀

IMPC - ICS

decreased prepulse inhibition ( J:211773 )

IMPC - ICS

reproductive system

small testis ( J:211773 )

♂

IMPC - ICS

female infertility ( J:211773 )

♀

IMPC - ICS

male infertility ( J:211773 )

♂

IMPC - ICS

vision/eye

abnormal retina morphology ( J:211773 )

IMPC - ICS

abnormal retina outer nuclear layer morphology ( J:211773 )

♀

IMPC - ICS

decreased total retina thickness ( J:211773 )

IMPC - ICS