All Phenotypes P2ry2<tm1c(EUCOMM)Hmgu> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

P2ry2^{tm1c(EUCOMM)Hmgu}
targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
MGI:5792951

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	P2ry2^{tm1c(EUCOMM)Hmgu}/P2ry2^{tm1c(EUCOMM)Hmgu} Tg(Tek-icre/ERT2)1Soff/0	B6N.Cg-P2ry2^{tm1c(EUCOMM)Hmgu} Tg(Tek-icre/ERT2)1Soff	MGI:5800452

Allelic Composition	P2ry2^{tm1c(EUCOMM)Hmgu}/P2ry2^{tm1c(EUCOMM)Hmgu} Tg(Tek-icre/ERT2)1Soff/0
Genetic Background	B6N.Cg-P2ry2^{tm1c(EUCOMM)Hmgu} Tg(Tek-icre/ERT2)1Soff
Cell Lines	HEPD0557_7_B07

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
P2ry2^{tm1c(EUCOMM)Hmgu} mutation (0 available); any P2ry2 mutation (18 available)
Tg(Tek-icre/ERT2)1Soff mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

increased susceptibility to hypertension ( J:224523 )

decreased vasodilation ( J:224523 )

• almost complete lost of dilation in response to flow

• however, vasodilation in response to sodium nitroprusside and vasoconstriction in response to phenylephrine are normal

muscle

decreased vasodilation ( J:224523 )

• almost complete lost of dilation in response to flow

• however, vasodilation in response to sodium nitroprusside and vasoconstriction in response to phenylephrine are normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/07/2024 MGI 6.23