Phenotypes associated with this allele

• Allele Symbol: Tubgcp4^em1(IMPC)J
• Allele Name: endonuclease-mediated mutation 1, Jackson
• Allele ID: MGI:5792574
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tubgcp4^em1(IMPC)J/Tubgcp4^em1(IMPC)J	C57BL/6NJ-Tubgcp4^em1(IMPC)J/J	MGI:6263795
ht2	Tubgcp4^em1(IMPC)J/Tubgcp4^+	C57BL/6NJ-Tubgcp4^em1(IMPC)J/J	MGI:6461781

Genotype
MGI:6263795

hm1

• Allelic Composition: Tubgcp4^em1(IMPC)J/Tubgcp4^em1(IMPC)J
• Genetic Background: C57BL/6NJ-Tubgcp4^em1(IMPC)J/J

Data Sources

IMPC Data for Tubgcp4

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

increased cell death ( J:279207 )

• blastocysts show apparent cell death after 3 days in culture

embryo

failure of blastocyst to hatch from the zona pellucida ( J:279207 )

• blastocysts fail to hatch from the zona pellucida with apparent cell death after 3 days in culture

mortality/aging

embryonic lethality prior to organogenesis ( J:211773 )

IMPC - JAX

embryonic lethality between implantation and somite formation, complete penetrance ( J:279207 )

• normal blastocysts are recovered at lower than expected Mendelian ratios at E3.5 (15% versus 25%); no homozygous embryos are recovered at E7.5

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:6461781

ht2

• Allelic Composition: Tubgcp4^em1(IMPC)J/Tubgcp4⁺
• Genetic Background: C57BL/6NJ-Tubgcp4^em1(IMPC)J/J

Data Sources

IMPC Data for Tubgcp4

behavior/neurological

hyperactivity ( J:211773 )

♂

IMPC - JAX