Tubgcp4em1(IMPC)J
Endonuclease-mediated Allele Detail
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Symbol: |
Tubgcp4em1(IMPC)J |
Name: |
tubulin, gamma complex component 4; endonuclease-mediated mutation 1, Jackson |
MGI ID: |
MGI:5792574 |
Synonyms: |
Tubgcp4em1J |
Gene: |
Tubgcp4 Location: Chr2:121001135-121029251 bp, + strand Genetic Position: Chr2, 60.37 cM, cytoband F1
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Alliance: |
Tubgcp4em1(IMPC)J page
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IMPC: |
Tubgcp4 gene page |
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Strain of Origin: |
C57BL/6NJ
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Project Collection: |
IMPC
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: This allele from project Tubgcp4-7966J-M7404 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences GACTATATAGACATCTTGGG, TTCTGTAACCTAGATTGATA, TCCGTAAGTATTGGGAATAG and TCCCAATACTTACGGAAGCC, which resulted in a 204 bp deletion beginning at Chromosome 2 positive strand position 121,178,575 bp GGGAGGGACTATATTAGCTA, and ending after GGCTTCCGTAAGTATTGGGA at 121,178,778 bp (GRCm38/mm10). This mutation deletes exon 6 and 124 bp of flanking intronic sequence including the splice acceptor and donor, and is predicted to cause a change of amino acid sequence after residue 147 and early truncation 10 amino acids later.
(J:188991)
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Inheritance: |
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Not Specified |
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
3 reference(s) |
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